<div class="wrapper">
  <div class="box a">A</div>
  <div class="box b">B</div>
  <div class="box c">C</div>
  <div class="box d">D</div>
  <div class="box e">E</div>
  <div class="box f">F</div>
</div>
body {
  margin: 40px;
}

.wrapper {
		display: grid;
    grid-gap: 10px;
		grid-template-columns: repeat(5, [col] 100px ) ;
		grid-template-rows: repeat(3, [row] auto  );
		background-color: #fff;
		color: #444;
	}

	.box {
		background-color: #444;
		color: #fff;
		border-radius: 5px;
		padding: 20px;
		font-size: 150%;
		z-index:10;

	}

	.a {
		grid-column: col / span  2;
		grid-row: row ;
	}
	.b {
		grid-column: col 3 / span  3 ;
		grid-row: row ;
	}
	.c {
		grid-column: col ;
		grid-row: row 2 ;
	}
	.d {
		grid-column: col 2 / span  3 ;
		grid-row: row 2 ;
	}

	.e {
		grid-column: col / span  5;
		grid-row: row 3;
	}

	.f {
		grid-column: col 3 / span 3;
		grid-row: row 2  ;
		background-color: rgba(49,121,207, 0.5);
    z-index: 20;
	}

External CSS

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External JavaScript

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