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HTML

              
                <h3>A Simple AJAX Example <span>with</span> Plain JavaScript</h3>
<p>Data retrieved from <a href="https://en.wikipedia.org/wiki/Albert_Einstein" target="_blank">Wikipedia</a></p>
<div>
  <img src="https://s3-us-west-2.amazonaws.com/s.cdpn.io/162656/Einstein.jpg" alt="Einstein">
  <button id="request">Learn more about Einstein</button>
  <div id="bio"></div>
</div>
              
            
!

CSS

              
                /* GENERAL STYLES
–––––––––––––––––––––––––––––––––––––––––––––––––– */

$bg-main-color: #fdfdfd;

* {
  box-sizing: border-box;
  font-family: sans-serif;
}

html {
    font-size: 1em;
}

body {
  background: $bg-main-color;
  line-height: 1.625;
}

h3, p, div {
  text-align: center;
}

h3 {
  text-transform: capitalize;
  span {
    text-transform: none;
  }
}

button {
  display: block;
  margin: 15px auto;
}

#bio {
  max-width: 70%;
  margin: 15px auto;
  padding: 10px;
}

              
            
!

JS

              
                (function() {
  
  'use strict';
    
  // find the desired selectors
  var btn = document.getElementById('request');
  var bio = document.getElementById('bio');
  
  // set up a request
  var request = new XMLHttpRequest();
  
  // keep track of the request
  request.onreadystatechange = function() {
    // check if the response data send back to us 
    if(request.readyState === 4) {
      // add a border
      bio.style.border = '1px solid #e8e8e8';
      // uncomment the line below to see the request
      // console.log(request);
      // check if the request is successful
      if(request.status === 200) {
        // update the HTML of the element
        bio.innerHTML = request.responseText;        
      } else {
        // otherwise display an error message
        bio.innerHTML = 'An error occurred during your request: ' +  request.status + ' ' + request.statusText;
      }
    }
  }

  // specify the type of request
  request.open('Get', 'https://s3-us-west-2.amazonaws.com/s.cdpn.io/162656/Bio.txt');

  // register an event
  btn.addEventListener('click', function() {
    // hide the button
    this.style.display = 'none';
    // send the request
    request.send();
  });
  
})();
              
            
!
999px

Console