<section class="grid">
  <div class="item">item1</div>
  <div class="item">item2</div>  
  <div class="item">item3</div>
  <div class="item">item4</div>
  <div class="item">item5</div>
</section>

.grid {
  display: grid;
  grid-auto-columns: minmax(60px, 200px);
  grid-auto-rows: 60px;
  grid-gap: 20px;
}


.item:first-child {
  grid-row-end: span 2;
}

.item:nth-child(2) {
  grid-column: 1 / span 2;
}

.item:nth-child(5) {
  grid-column: 3;
}



body {
  padding: 20px;
}