<div id="block">Тицяй, щоб уввімкнути або зупинити анімацію</div>
#block {
  font-family: monospace;
  background-color: gold;
  color: #222;
  font-size: 16px;
  line-height: 1.45;
  width: 175px;
  text-align: center;
  padding: 36px 16px;
  box-shadow: 1px 1px 1px 1px #000;
  cursor: pointer;
  transition: box-shadow .15s linear;
  position: absolute;
  top: 16px;
  left: 16px;
  animation: move 1.15s ease-in 0s infinite alternate paused none;
}

#block:hover {
  box-shadow: 1px 1px 1px 1px rgba(0, 0, 0, .45);
}

@keyframes move {
  from {
    top: 16px;
    left: 16px;
  }
  to {
    top: 250px;
    left: 350px;
  }
}
document.getElementById('block').onclick = function() {
  if ( this.style.animationPlayState != 'running' ) {
    this.style.animationPlayState = 'running';
  } else {
    this.style.animationPlayState = 'paused';
  }
}

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