<user-card>
  <div slot="username">
    <div>John Smith</div>
  </div>
</user-card>

<script>
customElements.define('user-card', class extends HTMLElement {
  connectedCallback() {
    this.attachShadow({mode: 'open'});
    this.shadowRoot.innerHTML = `
      <style>
      ::slotted(div) { border: 1px solid red; }
      </style>
      Name: <slot name="username"></slot>
    `;
  }
});
</script>